Is cold plasma better than microneedling?

Cold plasma (non-thermal plasma) is an ionized gas generated at room temperature, used for therapeutic, sterilization, and surface treatment purposes without heat damage. It creates active reactive oxygen and nitrogen species that destroy pathogens, stimulate tissue regeneration, and aid in Acne treatment, wound healing, and oncology by killing cancer cells.

Key Applications of Cold Plasma

• Skin Care & Dermatology:Used to treat acne, fine lines, and chronic skin diseases like eczema or psoriasis by stimulating collagen and balancing sebum.
• Medical & Surgical:Offers sterilization of wounds, and is used in tissue cutting and coagulation (e.g., Canady Helios systems).
• Oncology:Researched for its ability to induce apoptosis in tumor cells, as discussed in this PubMed study.
• Food Safety:Acts as a disinfectant to inactivate microorganisms on food surfaces and extends shelf life by retaining nutrients.
• Dental:Applied for biofilm removal and dental cleaning.

How It Works
Cold plasma, such as Cold Atmospheric Plasma (CAP), uses electrical energy to create an ionized gas (plasma) while maintaining low temperatures. This process, often generated by dielectric barrier discharges, creates reactive ions that pass through skin pores to enhance the immune barrier, improve product absorption, and boost fibroblast regeneration.

Benefits

• Non-invasive:Provides a comfortable treatment experience.
• Non-thermal:Prevents burning or damage to surrounding healthy tissues.
• Highly effective:Strong sterilization properties and stimulates rapid tissue repair.

Cold Plasma: What Is It and Why Use It?

Cold plasma, sometimes called non-thermal plasma, is one of the newest cutting edge medical concepts, but what is it?  Plasma is not a thing.  A table is a thing – it has substance and you can put your hands on it.  Plasma is a fundamental state of matter, explains FusEDWeb.  Along with liquids, solids and gases, it is one of four states of matter that exist in the universe.

Plasma is created by changing something else.  For example, if you heat a certain type of gas, you excite the molecules until they produce light, as in neon light, or in a modified version, a plasma TV display.  When you heat the gas, you create a plasma, something that acts like gas, but is able to conduct electricity.  It’s the electricity applied to that gas that produces a plasma and, therefore, the plasma light.

How does all of this fit into a medical concept?  Cold plasma applies that same basic theory to helium atoms, but at a lower level.  This creates a beam that is cool, hence the term non-thermal plasma.

What is It Used For?

Cold plasma has many different uses in a medical environment.  A study conducted by researchers at the Gamaleya Institute of Epidemiology and Microbiology found that it can kill certain types of microbes, meaning it helps fight infection.

The study authors applied a non-thermal plasma torch to two forms of bacteria, including a common staphylococcus, and were able to kill 99 percent of the organisms growing in a Petri dish.  This is exciting science as resistance to antibiotics is becoming more prevalent in the world arena.

Cold physical plasma - a new era in medicine

Definition of plasma

Looking at the star-studded sky we see – plasma! As a fact, more than 99 % of our visible universe is in the plasma state.

Plasma is the name of a special excited state of a gas, which is also called the fourth aggregate state next to solid, liquid and gaseous, and should not be confused with the liquid, cell-free blood component.

The input of energy transforms solid matter first into a liquid, then into a gas and further energy transfer induces plasma.

During this process, the mobility of the atoms and molecules forming the substance is increased until they reach free mobility in the gaseous state.

If additional energy in the form of heat or strong electric fields is applied to a gas, the particles reach partial or full ionisation, i.e. the extraction of electrons from the atoms or molecules of the gas. The resulting particles are freely moving electrons and ionised atoms. This makes plasma an electrically conductive medium.

Does cold plasma really work?

Yes, cold atmospheric plasma (CAP) works effectively, acting as a powerful tool in dermatology for acne, skin rejuvenation, and sterilization by using ionized gas to kill bacteria and stimulate tissue regeneration. It is safe for skin contact, typically operating at 35–40°C, and helps reduce inflammation and boost collagen.

What is the difference between PRP and cold plasma?

Platelet Rich Plasma (or PRP) uses plasma from a patient's body to rejuvenate their skin. Cold Plasma, in comparison, doesn't use any blood. The plasma in PRP is physiological plasma which comes from the body, whereas the plasma used in Cold Plasma is a physical plasma.

Is cold plasma better than microneedling?

For acne scars or enlarged pores: Microneedling tends to produce stronger results by physically disrupting scar tissue and encouraging new growth. Ideal for post-acne scarring solutions. For sagging skin or loss of firmness: Plasma is preferred, particularly around delicate areas like the eyes or jawline.

Who is a good candidate for cold plasma?

Ideal candidates include: People with acne or rosacea: Its antimicrobial and anti-inflammatory properties help calm breakouts and redness Those with aging skin: It boosts collagen, tightens skin, and reduces fine lines Patients with chronic wounds: CAP accelerates healing and reduces infection risk Individuals with ...